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Ursprungligen framställdes det av stenkol och andra kemiska föreningar och fann snabbt användning inom medicin och färgning.\u003c\/p\u003e\u003cp\u003eSärskilt intressant är att metylenblått tidigare användes som antiseptikum och för behandling av olika sjukdomar. Inom homeopatin uppskattas Methylenum caeruleum på grund av sina speciella egenskaper. 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